Trouble shooting

  • Product not meeting specification (immediate Release/control release )
    • Dissolution/DT
    • Hardness
    • Friability
    • Assay/BU/CU
  • Processibility issue
    • Sticking/DT
    • Capping/lamination
    • Punch jamming
    • Weight variation
    • Flow
    • Tool design/damage
  • Market complaint
  • OOT /OOS results
  • Very slow process